Opportunity Information: Apply for RFA DK 20 013
The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) Atlas Projects funding opportunity (RFA-DK-20-013) is a National Institutes of Health (NIH) cooperative agreement program that supports research teams in generating new molecular and anatomical data sets for inclusion in the GUDMAP database. The overall purpose is to expand and refine a community resource: a molecular anatomy atlas of developing mouse and human genitourinary tissues, with a strong emphasis on producing standardized, shareable atlas-quality data that can be broadly reused by the research community.
The scientific scope is narrowly focused on development and maturation of the kidney and lower urinary tract, specifically in human and mouse. Projects are expected to concentrate on (1) the lower urinary tract, including the ureters, bladder, urethra, prostate, and external male genitalia, and (2) the supporting and associated systems relevant to kidney and lower urinary tract biology, including vasculature, nerves, and lymphatics. In practical terms, the FOA is aimed at building detailed maps that connect tissue structures and cell types to molecular profiles during development, so that researchers can better understand how these organs form, mature, and change over time.
A central theme of the program is consortium-based work. Awardees become part of the broader GUDMAP consortium, meaning there is an expectation of coordination, data sharing, and alignment with consortium standards and priorities rather than fully independent, standalone projects. The long-term objective is to establish a comprehensive understanding of kidney and lower urinary tract development and maturation, which can then inform downstream research into tissue maturation and aging, congenital and developmental abnormalities (organ dysgenesis), disease mechanisms, and ultimately strategies for organ repair and regeneration. The FOA also notes that a separate companion solicitation supports a GUDMAP Data Hub (RFA-DK-20-014), indicating that atlas data generation projects and centralized data infrastructure are designed to work together.
From an administrative standpoint, the award mechanism is a U01 cooperative agreement, which typically reflects substantial NIH programmatic involvement in coordinating goals, milestones, and consortium activities. Clinical trials are not allowed under this announcement, reinforcing that the work is intended to be foundational, developmental, and atlas-building rather than interventional human research. The opportunity is categorized as discretionary funding, with an activity category aligned to health, and is associated with CFDA number 93.847. The listed award ceiling is $300,000, and the original application closing date was February 18, 2021 (meaning this specific posting reflects a past due date, though similar GUDMAP-related opportunities may recur under new numbers and dates).
Eligibility is broad and includes many types of U.S. organizations and institutions, such as public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), for-profit organizations (other than small businesses), small businesses, and multiple levels of government (state, county, city/township, special districts), as well as independent school districts and public housing authorities/Indian housing authorities. The FOA also explicitly highlights inclusion of a wide range of other eligible applicant groups and institution types, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), federally recognized tribal governments and other tribal organizations, U.S. territories or possessions, eligible federal agencies, faith-based or community-based organizations, and even non-U.S. (foreign) entities and regional organizations. This broad eligibility aligns with the program goal of building an extensive, high-impact atlas resource by drawing on diverse expertise, specimen access, and technical capabilities across many research settings.
In summary, this FOA funds consortium-driven atlas projects that produce high-value molecular and anatomical developmental maps of the kidney and lower urinary tract (including associated vessels, nerves, and lymphatics) in mouse and human, with the explicit intent that the resulting data will be deposited into and disseminated through the GUDMAP database as a lasting resource for the wider biomedical research community.Apply for RFA DK 20 013
- The National Institutes of Health in the food and nutrition, health sector is offering a public funding opportunity titled "GenitoUrinary Development Molecular Anatomy Project (GUDMAP) - Atlas Projects (U01 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847.
- This funding opportunity was created on 2020-11-23.
- Applicants must submit their applications by 2021-02-18. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $300,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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GUDMAP Atlas Projects (RFA-DK-20-013) FAQs
What is the GUDMAP Atlas Projects funding opportunity (RFA-DK-20-013)?
RFA-DK-20-013 is a National Institutes of Health (NIH) cooperative agreement funding opportunity that supports research teams in generating new molecular and anatomical datasets for inclusion in the GUDMAP database. The emphasis is on producing standardized, shareable, atlas-quality data intended for broad reuse by the research community.
What is the overall purpose of this program?
The program is designed to expand and refine a community resource: a molecular anatomy atlas of developing mouse and human genitourinary tissues. Projects are expected to generate high-value, standardized datasets that can be deposited into and disseminated through the GUDMAP database.
What scientific areas are included in the scope?
The scientific scope is narrowly focused on development and maturation of the kidney and lower urinary tract in human and mouse. The intent is to build detailed maps connecting tissue structures and cell types to molecular profiles over developmental time.
Which organs and anatomical regions are specifically targeted?
Projects are expected to concentrate on the lower urinary tract, including the ureters, bladder, urethra, prostate, and external male genitalia, as well as kidney development and maturation in mouse and human.
Are supporting systems (like blood vessels or nerves) included?
Yes. The FOA includes supporting and associated systems relevant to kidney and lower urinary tract biology, including vasculature, nerves, and lymphatics.
What types of outputs are expected from funded projects?
Funded projects are expected to generate new molecular and anatomical datasets that meet consortium standards and are suitable for inclusion in the GUDMAP database. The goal is atlas-quality, standardized, shareable data that can be broadly reused.
Is this opportunity intended for independent projects or consortium work?
This opportunity is consortium-based. Awardees become part of the broader GUDMAP consortium, and there is an expectation of coordination, data sharing, and alignment with consortium standards and priorities rather than fully independent standalone projects.
What does it mean that this is a cooperative agreement (U01)?
The award mechanism is a U01 cooperative agreement, which typically indicates substantial NIH programmatic involvement in coordinating goals, milestones, and consortium activities. Projects are expected to align with consortium needs and coordinated planning.
Are clinical trials allowed under this announcement?
No. Clinical trials are not allowed under this announcement, indicating the work is intended to be foundational and atlas-building rather than interventional human research.
How will the resulting data be shared?
The FOA indicates that the resulting atlas data are intended to be deposited into and disseminated through the GUDMAP database as a lasting community resource.
How does this FOA relate to the GUDMAP Data Hub?
The FOA notes a separate companion solicitation that supports a GUDMAP Data Hub (RFA-DK-20-014). This indicates atlas data generation projects and centralized data infrastructure are designed to work together, with projects generating datasets and the hub supporting data integration and dissemination.
What is the long-term objective of the program?
The long-term objective is to establish a comprehensive understanding of kidney and lower urinary tract development and maturation. This foundational understanding is intended to inform downstream research into tissue maturation and aging, congenital and developmental abnormalities (organ dysgenesis), disease mechanisms, and ultimately strategies for organ repair and regeneration.
What is the award mechanism and funding type?
The mechanism is a U01 cooperative agreement under NIH. The opportunity is categorized as discretionary funding, with an activity category aligned to health.
What is the CFDA number associated with this opportunity?
The opportunity is associated with CFDA number 93.847.
What is the maximum award amount (award ceiling) listed?
The listed award ceiling is $300,000.
When was the original application closing date?
The original application closing date listed for this specific posting was February 18, 2021.
Is this opportunity still open?
Based on the information provided, the listed application closing date (February 18, 2021) has passed, so this specific posting reflects a past due date. The description also notes that similar GUDMAP-related opportunities may recur under new numbers and dates.
Who is eligible to apply?
Eligibility is broad and includes many types of U.S. organizations and institutions, including public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), for-profit organizations (other than small businesses), small businesses, and multiple levels of government (state, county, city/township, special districts), as well as independent school districts and public housing authorities/Indian housing authorities.
Are minority-serving institutions and tribal organizations included in eligibility?
Yes. The FOA explicitly highlights a wide range of eligible groups, including Alaska Native and Native Hawaiian Serving Institutions, AANAPISIs, Hispanic-serving Institutions, HBCUs, TCCUs, federally recognized tribal governments and other tribal organizations, faith-based or community-based organizations, and U.S. territories or possessions.
Are non-U.S. (foreign) entities eligible?
Yes. The FOA explicitly includes non-U.S. (foreign) entities and regional organizations among eligible applicant types.
What is the primary tissue/organism focus for atlas building?
The atlas focus is on developing and maturing genitourinary tissues in mouse and human, particularly kidney and lower urinary tract, including relevant associated systems such as vasculature, nerves, and lymphatics.
What makes the data "atlas-quality" in this program?
Based on the FOA description, atlas-quality data are standardized, shareable datasets generated to consortium standards so they can be broadly reused and integrated into the GUDMAP molecular anatomy atlas resource.
What is the intended impact for the broader research community?
The intended impact is to provide a high-value, reusable molecular anatomy atlas resource that helps researchers understand organ formation, maturation, and changes over time, enabling downstream work related to development, abnormalities, disease mechanisms, and regeneration strategies.
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