Opportunity Information: Apply for RFA AI 21 078
The RePORT International Coordinating Center (RICC) funding opportunity (RFA AI 21 078) is a National Institutes of Health (NIH) cooperative agreement (U01) focused on supporting a single, centralized coordinating center for the global Regional Prospective Observational Research in Tuberculosis (RePORT) networks. The overall goal is to strengthen and align tuberculosis (TB) and TB/HIV observational research across multiple regions by providing coordination, shared infrastructure, and consistent operational support. In practical terms, the RICC is meant to function as the hub that helps the various RePORT network sites work together more efficiently, produce higher-quality data, and accelerate progress in TB and TB/HIV science through better collaboration and harmonization. The FOA explicitly indicates "Clinical Trial Not Allowed," signaling that the work supported under this award should be centered on observational research coordination and related enabling activities rather than interventional clinical trials.
The mission of the global RePORT networks, which the RICC is expected to advance, includes improving regional and international TB and TB/HIV research, building sustainable research capacity, strengthening infrastructure, and fostering collaboration among partners. The coordinating center is therefore positioned as both a scientific and operational enabler: it is expected to coordinate planning and implementation of research activities across the networks and to establish and maintain the core infrastructure required to carry out those activities. This infrastructure emphasis typically implies cross-network systems and processes that allow sites to collect, manage, share, and analyze observational data in consistent ways, along with mechanisms for communication, governance support, and coordination of multi-site scientific efforts.
Because this is a cooperative agreement, the NIH will generally have substantial programmatic involvement compared with a traditional grant mechanism. In a U01 structure, awardees often work closely with NIH staff on key aspects of project direction, coordination priorities, and performance expectations, reflecting the collaborative nature of a network-wide coordinating center. The activity category is Health, and the listed CFDA number is 93.855, placing it within NIH's broader health research support portfolio.
Eligibility is broad and includes a wide range of domestic and international organizations. Eligible applicants listed in the source include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations that are not federally recognized governments; public housing authorities/Indian housing authorities; nonprofit organizations with and without 501(c)(3) status (other than institutions of higher education); for-profit organizations (other than small businesses); small businesses; and other entities. The FOA also calls out additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, non-domestic (non-U.S.) entities (foreign organizations), regional organizations, Indian/Native American tribal governments other than federally recognized, and U.S. territories or possessions. This wide eligibility reflects the global and collaborative nature of TB research and the need for coordination that can span different institutional types and geographies.
Key administrative details from the listing include the opportunity category being discretionary, the funding instrument being a cooperative agreement, and the agency being NIH. The opportunity was created on 2021-11-02, and the original closing date is listed as 2022-03-17. The award ceiling and expected number of awards are not specified in the provided source data, which commonly means applicants would need to consult the full FOA text (or related NIH budget guidance) to understand anticipated budget ranges, allowable costs, and the scale of the coordinating center activities NIH intends to support.
Overall, this opportunity is designed to fund a coordinating center that can provide the backbone for multi-country, multi-site observational TB and TB/HIV research efforts. Rather than funding a single research study in isolation, it focuses on enabling and organizing research across the entire RePORT network ecosystem by standardizing approaches, supporting shared infrastructure, and improving collaboration so that regional and international partners can generate more comparable, higher-impact scientific outputs.Apply for RFA AI 21 078
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "RePORT International Coordinating Center (RICC) (U01 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855.
- This funding opportunity was created on 2021-11-02.
- Applicants must submit their applications by 2022-03-17. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the RePORT International Coordinating Center (RICC) funding opportunity?
This opportunity (RFA AI 21 078) is a National Institutes of Health (NIH) cooperative agreement (U01) to support a single, centralized coordinating center for the global Regional Prospective Observational Research in Tuberculosis (RePORT) networks.
What is the main purpose of the RICC award?
The purpose is to strengthen and align tuberculosis (TB) and TB/HIV observational research across multiple regions by providing coordination, shared infrastructure, and consistent operational support so network sites can collaborate more effectively, produce higher-quality data, and accelerate progress in TB and TB/HIV science.
How does the RICC function in practical terms?
The RICC is intended to operate as a hub that helps RePORT network sites work together more efficiently through harmonized operations, cross-network coordination, and infrastructure support that improves consistency in how observational data are collected, managed, shared, and analyzed.
Is this opportunity intended to fund a single research study?
No. The opportunity is designed to fund a coordinating center that enables and organizes observational research across the RePORT network ecosystem, rather than funding a single stand-alone research study.
Are clinical trials allowed under this funding opportunity?
No. The funding opportunity explicitly indicates "Clinical Trial Not Allowed," meaning the supported work should focus on observational research coordination and enabling activities, not interventional clinical trials.
What type of research does this coordinating center support?
The focus is on observational TB and TB/HIV research across multiple regions, with an emphasis on coordination, harmonization, and shared infrastructure to improve comparability and impact of research outputs.
What is meant by "global RePORT networks" in this context?
The global RePORT networks refer to multi-region, multi-site observational TB and TB/HIV research networks. The RICC is expected to advance their mission by improving regional and international research, building sustainable capacity, strengthening infrastructure, and fostering collaboration among partners.
What are the coordinating center's expected roles?
The RICC is positioned as both a scientific and operational enabler. It is expected to coordinate planning and implementation of research activities across networks and establish and maintain core infrastructure needed to carry out those activities.
What kinds of "core infrastructure" are implied by this opportunity?
Based on the description, core infrastructure typically includes cross-network systems and processes that support consistent observational data collection, data management, data sharing, and analysis, along with mechanisms for communication, governance support, and coordination of multi-site scientific efforts.
What is the funding mechanism for this opportunity?
The mechanism is a cooperative agreement (U01), which generally involves substantial NIH programmatic involvement compared with traditional grant mechanisms.
What does it mean that this is a cooperative agreement (U01)?
In a U01 structure, awardees often work closely with NIH staff on key aspects of project direction, coordination priorities, and performance expectations. This reflects the collaborative, network-wide nature of a coordinating center.
Which agency is offering this opportunity?
The agency is the National Institutes of Health (NIH).
What is the opportunity category?
The opportunity category is discretionary.
What is the activity category listed for this opportunity?
The activity category is Health.
What is the CFDA number associated with this opportunity?
The listed CFDA number is 93.855.
How many awards will NIH make under this opportunity?
The expected number of awards is not specified in the provided information.
What is the maximum award amount (award ceiling)?
The award ceiling is not specified in the provided information.
When was this opportunity created?
The opportunity was created on 2021-11-02.
What is the original closing date for applications?
The original closing date is listed as 2022-03-17.
Who is eligible to apply?
Eligibility is broad and includes many domestic and international organization types, such as government entities, institutions of higher education, nonprofits (with or without 501(c)(3) status), for-profit organizations (other than small businesses), small businesses, tribal governments and tribal organizations, public housing authorities/Indian housing authorities, and other entities.
Are non-U.S. (foreign) organizations eligible?
Yes. Non-domestic (non-U.S.) entities (foreign organizations) are listed as eligible applicants.
Are U.S. territories or possessions eligible to apply?
Yes. U.S. territories or possessions are explicitly included among eligible applicant categories.
Are tribal entities eligible to apply?
Yes. Federally recognized Native American tribal governments are eligible, and the listing also includes Indian/Native American tribal governments other than federally recognized, as well as Native American tribal organizations that are not federally recognized governments.
Are minority-serving institutions included in eligible applicant types?
Yes. The listing calls out Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are included among the eligible applicant categories.
Are federal agencies eligible to apply?
Yes. Eligible federal agencies are listed among the eligible applicant categories.
Does the opportunity emphasize collaboration across regions?
Yes. A central aim is to improve collaboration and harmonization across multiple regions so that TB and TB/HIV observational research efforts are better aligned and more comparable.
What kinds of outcomes is the RICC intended to improve?
The opportunity is intended to improve efficiency across sites, increase data quality, enhance collaboration, and accelerate scientific progress in TB and TB/HIV by standardizing approaches and supporting shared infrastructure across the networks.
Where can applicants find budget ranges or allowable cost details?
The provided information does not specify the award ceiling or number of awards. In such cases, applicants typically need to consult the full FOA text (or related NIH budget guidance) for anticipated budget ranges, allowable costs, and the intended scale of coordinating center activities.
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