Opportunity Information: Apply for CDC RFA JG 25 0083

This funding opportunity (CDC RFA JG 25 0083) is a PEPFAR-supported cooperative agreement from the Centers for Disease Control and Prevention (CDC) that focuses on providing hands-on technical assistance to the Botswana Ministry of Health (MOH). The core purpose is to help Botswana implement national HIV and TB policies and strengthen comprehensive HIV care and treatment services across the full clinical cascade, with a strong emphasis on children, adolescents, and young people living with HIV, as well as pregnant and breastfeeding women and their children. A key theme running through the announcement is improving both service quality and program performance so that Botswana can close remaining gaps toward the UNAIDS 95-95-95 targets, particularly for younger age groups where diagnosis, treatment initiation, and sustained viral suppression can lag behind adults.

The program is designed to address practical, real-world barriers that affect HIV/TB outcomes in these priority populations. On the clinical side, the work aims to strengthen case finding and ensure that once clients are identified, they receive high-quality care and treatment that is consistent, continuous, and measurable. The NOFO highlights the need to improve HIV/TB service delivery specifically for children and adolescents, who often face unique challenges related to disclosure, adherence, transition from pediatric to adult care, and retention in care. It also prioritizes support for pregnant and breastfeeding women and their children, reflecting the ongoing need to maintain strong maternal HIV services and prevent negative outcomes for mothers and infants throughout pregnancy and breastfeeding.

A major component of the requested technical assistance is capacity building and clinical mentorship for healthcare workers. This includes improving provider skills and confidence to deliver quality HIV/TB services tailored to children, adolescents, and pregnant or breastfeeding women, and strengthening routine clinical practices that support better outcomes at each step of the cascade. The expectation is not simply classroom-style training, but ongoing mentorship and practical support that helps facilities implement national guidelines consistently, troubleshoot service delivery problems, and maintain standards of care over time.

Another central element is integrating mental health and psychosocial support into routine HIV/TB services, with a particular focus on adolescents and young people living with HIV. The NOFO recognizes that clinical outcomes are closely tied to mental health, stigma, social support, and the realities of adolescent development. In practice, this means helping the MOH and service delivery sites embed mental health and psychosocial supports into standard HIV/TB care rather than treating them as optional add-ons. The intended result is more comprehensive care that improves retention and adherence, supports viral suppression, and responds to the broader needs of young clients navigating school, relationships, family dynamics, and disclosure.

The opportunity also emphasizes strengthening national policy development and implementation to improve quality and expand access to comprehensive care and treatment services. This includes technical support to refine or operationalize national policies, translate them into workable service delivery approaches, and reinforce quality improvement systems so that policy changes lead to measurable improvements in care. Alongside policy and service delivery, the NOFO explicitly calls out HIV/TB data quality challenges among children, adolescents, and young people. Improving data quality is positioned as a necessary step for identifying gaps, targeting interventions, monitoring progress toward 95-95-95, and ensuring that program decisions are based on reliable information.

In funding terms, CDC anticipates approximately $1,500,000 in total funding for the first year, subject to availability of funds. The award ceiling is listed as $0 for Year 1, which typically signals that the agency is not setting a fixed per-award cap in the notice even though it has an estimated total amount available. CDC expects to make up to two awards. The instrument type is a cooperative agreement, meaning recipients should anticipate substantial CDC involvement, collaboration, and ongoing technical engagement rather than a hands-off grant structure.

Eligibility is broad and includes various levels of government, public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), for-profit organizations (including small businesses), tribal governments and organizations, and other unrestricted applicants. The CFDA number is 93.067, and the original closing date listed for applications is February 19, 2025. Overall, the opportunity is aimed at organizations capable of delivering high-impact technical assistance to a national ministry, strengthening frontline clinical practice and mentorship, integrating mental health and psychosocial supports into HIV/TB care, improving data quality, and helping Botswana reduce HIV/TB-related morbidity and mortality among children, adolescents, and mothers while moving closer to the 95-95-95 goals.

  • The Centers for Disease Control-GHC in the health sector is offering a public funding opportunity titled "Provide technical assistance to the Botswana Ministry of Health to implement HIV/TB policies and services for children and adolescents living with HIV including mental health and psychosocial support and pregnant and breastfeeding women under PEPFAR" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
  • This funding opportunity was created on 2024-12-03.
  • Applicants must submit their applications by 2025-02-19. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 2 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Unrestricted.
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